This content has not been reviewed within the past year and may not represent Web MD's most up-to-date information. To find the most current information, please enter your topic of interest into our search box. The new warnings apply to fluoroquinolones, a class of antibiotics that includes the popular drug Cipro. The FDA has told companies that the drugs must now carry "black box" warnings alerting doctors and patients that the drugs can increase risk of tendinitis and tendon rupture in some patients. Fluoroquinolones have carried similar warnings for years, but officials say they continue to receive reports of safety problems. A "black box" warning is the FDA's sternest warning. "We have seen continuing reports of tendon rupture so we are trying to increase awareness," says Edward Cox, MD, director of the FDA's Office of Antimicrobial Products. The warning applies to drugs of the fluoroquinolone class, including Cipro, Cipro XR, Proquin XR, Levaquin, Floxin, Noroxin, Avelox, Factive, and marketed generics. UPDATE: A few months after this article was posted, the work by Baylor researchers has begun to have international impact. The use of ciprofloxacin and other antibiotics of the class of fluoroquinolones may be associated with disruption of the normal functions of connective tissue, including tendon rupture, tendonitis and retinal detachment. These observations reported in a number of journals resulted in the drugs currently having a black box warning physicians and patients of the potential deleterious side effects. The endothelium, the thin layer of cells that line our arteries and veins, is like a gatekeeper, controlling the movement of materials into and out of the bloodstream. Endothelial cells are held tightly together by specialized proteins that function like strong ropes (red) and others that act like cement (blue). NIH Image Gallery “A natural tissue to worry about is the aorta, a blood vessel that relies heavily on having a sound connective tissue component – called the extracellular matrix – to maintain its integrity,” said first author Dr. Le Maire, director of research in the division of cardiothoracic surgery, vice-chair for research and professor of surgery and of molecular physiology and biophysics at Baylor College of Medicine. Two retrospective clinical studies looked at the possible association between fluoroquinolones and cardiovascular problems. “They found that patients who received fluoroquinolones had a higher risk for aneurysms (formation of balloon-like areas in the aorta that weaken the integrity of the vessel), ruptures or dissections (tears in the wall) than patients who did not receive the antibiotics. Will zoloft help me lose weight Order neurontin online Lasix resistance Order viagra online with paypal Cipro is an antibiotic manufactured by Bayer that has been linked to serious side effects, such as nerve damage, tendon ruptures, allergic reactions, and a. May 23, 2018. Several lawsuits are in the courts alleging systemic malfeasance on the part. Should you avoid exercise or exercise more on Ciprofloxacin ? Jul 8, 2008. FDA Warning Cipro May Rupture Tendons. A consumer watchdog group sued the FDA in January asking for the new warnings. The agency. More than 25 million fluoroquinolone antibiotic prescriptions are filled every year in the U. alone by people who are suffering common illnesses like urinary tract infections, bronchitis, and sinus infections. In fact, fluoroquinolone antibiotics like Levaquin, Cipro, and Avelox are just a few of the most commonly prescribed medications for those types of illnesses. Though Levaquin and other medications in this class should be used a secondary treatment for infections that are particularly difficult to heal, they are instead being overprescribed as first-line treatments of simple common infections. One of the biggest concerns with the use of these drugs is the host of serious side effects that they are associated with including vision problems, tendon injuries, nerve damage, and potentially fatal internal complications. The goal of this report is to help you understand the serious side effects that have been associated with fluoroquinolones like Levaquin and explore the options that may be available to you or your loved ones who have been injured by these drugs. First, it’s important to know that Levaquin is not the only fluoroquinolone antibiotic that carries these dangerous side effects, other drugs include –Researchers have shown that fluoroquinolone antibiotics like these can damage collagen proteins.[i] Collagen is found in connective tissue, skin and tendons, muscles, and even bones. Unfortunately, the breakdown of collagen can cause a host of serious physical issues, including –An aortic aneurysm is a potentially fatal condition in which a weak spot develops in the wall of the main artery of the body. The product liability lawyers at Saiontz & Kirk, P. are reviewing potential lawsuits for users of Cipro who have been diagnosed with peripheral neuropathy, a painful and potentially permanent form of nerve damage associated with the popular antibiotic. Ciprofloxacin lawsuits Aortic Aneurysm Lawsuits - Levaquin and Cipro News & FAQs, Fluoroquinolone Trouble Untangled In the Pipeline Metoprolol 50 mg er tab Ohio Product Liability Lawyer and Pharmaceutical Injury Attorney reviewing Cipro lawsuits and representing plaintiffs nationwide in fluoroquinolone antibiotic. Cipro Lawsuits & Antibiotic Injury Settlements - The Lyon Firm The.. FDA Warns That Cipro and Similar Antibiotics May Rupture Tendons. Cipro Injury Lawsuit Rottenstein Law Group LLP. Jul 25, 2018. Findings suggest that ciprofloxacin and other antibiotics of the same class should be used with caution in patients with aortic dilatation. Patients taking FQ antibiotics such as Levaquin, Cipro, Avelox, Noroxin. Lawsuits against the manufacturers of the fluoroquinolone antibiotics Avelox and. Jul 17, 2017. The first fluoroquinolone ciprofloxacin/Cipro came on the market in 1987, and since. The case was the first of about 2,600 similar lawsuits.