Tamoxifen for breast cancer treatment

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  1. RmllmR Moderator

    Tamoxifen for breast cancer treatment


    Breast cancer is a complex disease that’s different for every woman. Before you start a treatment, your doctor will want to know the size of the tumor and how far it has spread in your body, called the stage of the cancer. There are five basic stages, 0 through IV, and a number of sub-stages. Staging is a way for doctors to describe your condition. Tamoxifen and raloxifene have been shown to reduce the risk breast cancer, but they can have their own risks and side effects. Tamoxifen and raloxifene are the only drugs that are approved in the US to help lower the risk of breast cancer, although for some women, drugs called aromatase inhibitors might be an option as well. This means that they act against (or block) estrogen (a female hormone) in some tissues of the body, but act like estrogen in others. Estrogen can fuel the growth of breast cancer cells. Tamoxifen can be taken whether or not you have gone through menopause, but raloxifene is only approved for post-menopausal women. Both of these drugs block estrogen in breast cells, which is why they can be useful in lowering breast cancer risk. To lower the risk of breast cancer, these drugs are taken for 5 years. The effect of these drugs on breast cancer risk has varied in different studies. When the results of all the studies are taken together, the overall reduction in risk for these drugs is about 40% (more than a third). These drugs lower the risk of both invasive breast cancer and ductal carcinoma in situ (DCIS). Although a medicine that cuts your risk by about 40% sounds like it must be a good thing, what it would really mean for you depends on how high your risk is in the first place (your baseline risk).

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    Tamoxifen is a drug taken orally in pill form. For over a quarter of a century, physicians have prescribed tamoxifen to help treat patients with advanced breast cancer. Tamoxifen dosing information. Usual Adult Dose for Breast Cancer For the treatment of metastatic breast cancer in women and men 20 to 40 mg orally Dosages greater than 20 mg should be given in divided doses morning and evening. Tamoxifen is a hormone therapy drug used to treat ER+ breast cancer in pre- and post-menopausal women. Learn about how tamoxifen works and its side effects at Breast Cancer Care.

    Some types of breast cancer are affected by hormones in the blood. ER-positive and PR-positive breast cancer cells have receptors (proteins) that attach to estrogen, which helps them grow. There are different ways to stop estrogen from attaching to these receptors. Hormone therapy is a form of systemic therapy, meaning it reaches cancer cells almost anywhere in the body and not just in the breast. It's recommended for women with hormone receptor-positive (ER-positive and/or PR-positive) breast cancers, and it does not help women whose tumors are hormone receptor-negative (both ER- and PR-negative). Hormone therapy is often used after surgery (as adjuvant therapy) to help reduce the risk of the cancer coming back. Sometimes it is started before surgery (as neoadjuvant therapy) as well. Hormone therapy can also be used to treat cancer that has come back after treatment or that has spread to other parts of the body. It is usually given as an additional treatment following surgery, to reduce the risk of breast cancer returning in the same breast or a new breast cancer developing in either breast, or spreading somewhere else in the body. If you’re going to take tamoxifen as part of your treatment for primary breast cancer, your specialist will tell you when it’s best to start. Tamoxifen can be used to treat primary breast cancer. It may also be used to reduce the risk of breast cancer developing in women who have a significant family history of breast cancer. Back to top Tamoxifen may be prescribed if you have primary breast cancer, recurrence or secondary breast cancer. Find out more about how male breast cancer is treated. Most breast cancers in men are oestrogen receptor positive. If your cancer is found to be hormone receptor negative, then tamoxifen will not be of any benefit to you.

    Tamoxifen for breast cancer treatment

    Tamoxifen - Chemotherapy Drugs - Chemocare, Tamoxifen Uses, Dosage, Side Effects -

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  3. Jun 27, 2017. WebMD looks at the use of the drug tamoxifen for treating breast cancer and preventing it in high-risk cases.

    • Tamoxifen for Breast Cancer Treatment and Prevention - WebMD.
    • Tamoxifen Breast Cancer Care.
    • Tamoxifen and Raloxifene for Lowering Breast Cancer Risk.

    Tamoxifen Nolvadex is a medication used to treat hormone-receptor positive early and metastatic breast cancers and to reduce breast cancer risk in undiagnosed women at higher-than-average risk of developing breast cancer. Learn more about tamoxifen. Tamoxifen for breast cancer treatment is prescribed for 5-10 years. The length of treatment coupled with side effects, such as menopausal symptoms, can make it tough to complete tamoxifen therapy. Dealing with menopausal symptoms related to hormone therapy can be hard. Tamoxifen is the oldest of the hormonal therapies, drugs that block the effects of estrogen in the breast tissue. Tamoxifen is approved by the FDA to treat people diagnosed with both early-stage and advanced-stage hormone-receptor-positive breast cancer. Learn more about tamoxifen in pill form.

     
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